Sera from each group of animals were tested in a functional HIV neutralising TZM-bl assay.

Abstract

<p>The serum dilution that was able to achieve half maximal inhibition of HIV infectivity was higher in Group B (3 × ID + 2 × IN) for both a closely sequence matched Clade C virus CN54 (A) and a more sequence divergent Clade C HIV (B). All animals from this group achieved neutralisation compared to only 4 of the 7 animals in Group A (3 × IN + 2 × ID) (C).</p