Palladium-Catalyzed Oxidative
Heck Coupling Reaction
for Direct Synthesis of 4-Arylcoumarins Using Coumarins and Arylboronic
Acids
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Abstract
An efficient protocol for the direct synthesis of 4-arylcoumarins
via palladium-catalyzed oxidative Heck coupling reaction of coumarins
and arylboronic acids was developed. 4-Arylcoumarins were obtained
in moderate to excellent yields, and the reaction also showed tolerance
toward functional groups such as hydro, methoxy, diethylamino, nitro,
and chloro groups