Abstract

<p>Confocal microscopic images of L3, L4 and Adult stage of <i>N</i>. <i>brasiliensis</i> incubated with 20 μg/ml of rfhSP-D, biotin-conjugated anti-rfhSP-D, followed by streptavidin-cy3 <b>(a)</b>. 250 L4 stage larvae, coated or uncoated with rfhSP-D were intra-nasally administered into naïve mice. Intestinal worm burden <b>(b)</b>, detection by ELISA of IL-33, TSLP and IL-25 in the lung <b>(c)</b>, percentage of lung ILC2 and mean fluorescence intensity (MFI) of markers of alternative macrophage activation were quantified at day 5 PI. <b>(d)</b>. Data are representative of 4 individual experiments. N = 5–8 mice per group. *P<0.05, **P<0.01.</p

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