Highly Diastereoselective Synthesis of 1-Pyrrolines <i>via</i> SnCl<sub>4</sub>-Promoted [3 + 2] Cycloaddition between Activated Donor–Acceptor Cyclopropanes and Nitriles
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Abstract
Activated donor–acceptor cyclopropanes underwent formal [3 + 2] cycloaddition with nitriles in the presence of SnCl<sub>4</sub>. The product 1-pyrrolines were isolated as single <i>cis</i>-diastereomers in moderate to good yields
