Summary of 2-way ANOVA. Significance of time, group and time x group effects of conventional metabolic profiling in blood across 6, 12 and 24 months following diagnosis with IM. False discovery rates (FDR) were based on Storey [36] using the bootstrap (boot) and the polynomial (poly) fit methods to estimate lambda, as well as on by Benjamini and Hochberg [37] (BH). Table S2b. Summary of 2-way ANOVA. Significance of time, group and time x group effects for complete blood count (CBC) profiling in blood across 6, 12 and 24 months following diagnosis with IM. False discovery rates (FDR) were based on Storey [36] using the bootstrap (boot) and the polynomial (poly) fit methods to estimate lambda, as well as on by Benjamini and Hochberg [37] (BH). Table S2c. Summary of 2-way ANOVA. Significance of time, group and time x group effects for conventional differential blood count profiling in blood across 6, 12 and 24 months following diagnosis with IM. False discovery rates (FDR) were based on Storey [36] using the bootstrap (boot) and the polynomial (poly) fit methods to estimate lambda, as well as on by Benjamini and Hochberg [37] (BH). Basophil count was not considered due to a large proportion of missing values. Table S2d. Summary of 2-way ANOVA. Significance of time, group and time x group effects for standard endocrine profiling in blood with urine specific gravity and pH across 6, 12 and 24 months following diagnosis with IM False discovery rates (FDR) were based on Storey [36] using the bootstrap (boot) and the polynomial (poly) fit methods to estimate lambda, as well as on by Benjamini and Hochberg [37] (BH). (DOC 150 kb
