Community structure of patients with or without recurrent C. difficile infection. Principal coordinates analysis (PCoA) was used to plot the Yue and Clayton dissimilarity index (θ YC ). a The community structure of the microbiota in index (initial) samples from nonrecurrent, recurrent, and reinfected patients (analysis of molecular variance (AMOVA), p = 0.068). b The community structure of samples positive or negative for C. difficile as determined by cultivation (AMOVA, p = 0.001). (PDF 166 kb