<p>Two water molecules (W1 and W2) are demonstrating water bridged hydrogen bonds (red) in the <i>BD2-L10</i> complex. A single water mediated hydrogen bond is observed in the case of JQ1 (grey). Compound L10 is shown in yellow. The residues corresponding to <i>BD2-L10</i> and <i>BD2-JQ1</i> are shown in purple and grey, respectively. The ligands and the interacting residues are shown as sticks. Water molecules are shown as spheres. The hydrogen bonds are shown as broken lines.</p
