Several social issues, like aging, stimulate the use of mobile ICT applications for mobile healthcare (e.g., telemonitoring). To support novel m-health applications, the consequences of developing these applications should be considered in the scope of a comprehensive architecture. This paper describes ongoing research that focuses on developing an application framework for supporting the development of context-aware m-health applications. It gives initial requirements for such a framework and it gives a first attempt for a functional decomposition. The use of the framework is illustrated by means of an epilepsy tele-monitoring scenario