Boxplot of the dN/dS ratio calculated from the alignment of 9 primates including human, chimpanzee, gorilla, orangutan, gibbon, macaque, baboon, marmoset and bushbaby.
<p>The results of the Mann Whitney test showed that genes involved in several comorbid disorders have undergone more purifying selection than the genes uniquely associated with ASD. This observation is consistent with the GERP results in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0157937#pone.0157937.g004" target="_blank">Fig 4</a>.</p