Comparison of lesion size between wild-type mice and mice lacking macrophages at the inflammatory sites or in the systemic system at day 7 after laser injury.
<p>(A) Lesion size was significantly smaller in <i>CCR2</i><sup><i>−/−</i></sup> mice compared with WT mice and (B) in mice injected with clodronate liposomes compared with controls. (C) Representative micrographs of CNV (white arrows) in RPE-choroid flatmounts. Scale bars, 100 μm. *P < 0.05 with Wilcoxon rank-sum test. n = 8 for all groups.</p
