Abstract

<p>A) Damage score after inspection of 5 HPF at the corticomedullary border (control baseline n = 5, control 24 hours n = 6, GlcNAc baseline n = 11, GlcNAc 24 hours n = 14). Sections were evaluated in a blinded manner by an experienced nephropathologist. B)–D) Representative PAS stainings from kidneys before and after IR. (X 200) B) Uninephrectomy section from undamaged kidney. C) and D) Kidney sections 24 hours after the end of ischemia. Asterix marks vanishing or missing nuclei. Black arrows mark tubular casts consisting of tubular cells. Yellow arrows show necrotic areas and denuded tubuli with regions just consisting of naked basement membrane. C) Kidney from animal treated with twice oral gavage of 10% GlcNAc solution before IR. (D) Kidney from control animal with twice oral gavage of PBS before IR.</p

    Similar works

    Full text

    thumbnail-image

    Available Versions