Trifluoromethylseleno
substituent (CF<sub>3</sub>Se) is an emerging
group, but its direct introduction onto organic molecules is still
quite limited and mainly restricted to nucleophilic methods. Herein,
we describe a new approach to easily and safely perform electrophilic
trifluoromethylselenolation starting from a simple and easily accessible
reagent, namely, benzyltrifluoromethyl selenide. This strategy can
be generalized to various fluoroalkylselanyl groups, even functionalized
ones