Additional file 1: of A biologically informed method for detecting rare variant associations

Abstract

Script for generating reference sequence. Python script used to generate a reference sequence file for input into SeqSIMLA2 simulation software. The allele frequency file used in the script was obtained by parsing the protein coding regions of the autosomes in the 1000 Genomes Project VCF file. Additional specifications include the number of reference samples to generate and the number of markers to include in the reference file. (DOCX 14 kb

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