Quantitative analysis of necrotic area (A), mitosis index (B) ulceration (C) and bizarre cells (D) in slides of tumors from different groups stained with hematoxylin and eosin. The percentages (A, C) or absolute numbers (B, D) were calculated in triplicates in 10 fields with a 400× magnification. (One-Way ANOVA and a post-hoc Bonferroni’s multiple comparison test). (TIF 2723 kb