A new phenone from the roots of <i>Paeonia suffruticosa</i> Andrews

Abstract

<p>Thirteen phenones were obtained from the 70% ethanol extract of <i>Paeonia suffruticosa</i> Andrews. Their structures were determined on the basis of chemical methods and spectral data. Among them, compound <b>1</b> was identified as a new compound, and compounds <b>5</b> and <b>13</b> were obtained from genus <i>Paeonia</i> for the first time. The inhibitory effects of isolated compounds (<b>1</b>–<b>12</b>) on nitric oxide (NO) production in lipopolysaccharide-activated macrophages were evaluated, and NO production was suppressed significantly by compound <b>7</b>.</p

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