Bracci, E

pizzo, E

Vagnoni, E

van Ballegooijen, M

Wilschut, J

Cost-effectiveness analysis of a FOBT
based Colorectal Screening Programme
Bracci Enrico
1
, Pizzo Elena
2
, Vagnoni Emidia
1
, Wilschut Janneke
3
, van Ballegooijen Marjolein
3
Abstract
Colorectal cancer (CRC) is one of the most
common forms of cancer in western countries and
represents the second leading cause of cance
r mortality in Europe. Early detection and
removal of cancerous lesions can reduce the in
cidence of CRC, its mortality and improve
patients’ quality of life. The main literature on
this topic refers to USA and few studies have
been conducted in Italy to date.
Aim of the paper is to shed some light on
the effectiveness and costs of CRC screening
programs in the Italian health care system.
We use as case-study a Regional CRC screening pr
ogram to determine the full costs and the
effectiveness of the adopted techniqu
es, FOBT combined with colonoscopy.
The costs involved in each phase of the program
are valued using a micro-costing analysis.
Effectiveness is valued in terms of early
detected lesions and years of life gained. A
MISCAN-COLON Model© is used to simulate a
nd compare two alternative scenarios, with
or without the screening program, and estim
ate the costs for y
ear of life gained.
The preliminary results show that the screen
ing will prevent almost 1.700 deaths in 30 years
with an incremental cost eff
ectiveness ratio of € 2.388,63 for life year gained. The results
outpace those of previous studies, signalling an
increasing effectiveness of CRC screening
programme. Besides, the paper highlights the
importance of implementing a screening not
only for the effects that prevention can have
in clinical terms, but also for the economic
impact of such a policy in relation to the l
ong-term sustainability of healthcare systems

Cost-effectiveness analysis of a FOBT-based colorectal screening programme

Abstract

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