MOESM3 of PDGF-AA mediates mesenchymal stromal cell chemotaxis to the head and neck squamous cell carcinoma tumor microenvironment

Abstract

Additional file 3: Figure S4. The MSC markers gremlin-1 and CD105 are co-localized in the TM of patient with OCSCC (oral tongue). High power resolution confocal images from representative sections of human OCSCC specimens (A) demonstrate TM cells positive for the MSC markers anti-gremlin-1 (red) and anti-CD105 (green). An orange color on merged images indicates co-localization of gremlin-1 and CD105. In addition, TM MSCs were detected by anti-gremlin-1 (red) and anti-CD90 (blue). A magenta color on merged images indicates co-localization of gremlin and CD90 that did not co-localize with the hematopoietic marker, anti-CD45 (green) (B). The nuclei are depicted as grey

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