Expression of HDAC5 antigens in mice in the chronic amphetamine exposure groups. We compared total (file 4) or phosphorylated (file 5) HDAC5 in the NAc. (PDF 2600 kb

Christina Liu (171485)

Philip Liu (453985)

We observed several nuclear EDNs with a uniform diameter of 30 nm (A1, B1 & B2, arrowheads); three of these EDNs appeared on the membrane in tandem near the rough ER (A1). Only EDN larger than 60 nm appeared to be in the cytoplasm (B & B1, arrows). These unstained samples had reduced background noise, and we found EDNs (arrows) in the cytoplasm and nuclei. Although EDNs were visible, we cannot identify Ly/Ex, but can identify MG and N from the outline of their nuclei. Bars (microns) = 500 (A, A1 & B). (PDF 2836 kb

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Additional file 6: of Epigenetics of amphetamine-induced sensitization: HDAC5 expression and microRNA in neural remodeling

Expression of HDAC5 antigens in mice of acute amphetamine exposure groups. We compared total (file 2) or phosphorylated (file 3) HDAC5 in the NAc. (PDF 3461 kb

Additional file 3: of Epigenetics of amphetamine-induced sensitization: HDAC5 expression and microRNA in neural remodeling

Additional file 4: of Epigenetics of amphetamine-induced sensitization: HDAC5 expression and microRNA in neural remodeling

We conducted a gross comparison of the total locomotor activities, and compared changes in locomotion between AMPH-treated and saline-treated animals in various exposure paradigms (SAL vs. AMPH groups in acute exposure, SAL7/W/S vs. A7/W/A and SAL7/W/S vs A7/W/S [placebo] in chronic exposure groups). Using one-way ANOVA followed by Newman-Keuls Multiple Comparison test, we found that AMPH induced a significant main effect (p < 0.001), with an exception between the SAL7/W/S and A7/W/S groups (p > 0.05). The average rate of locomotion (in meters per hour) was 57 + 6 and 105 + 6 for A1 and A7/W/A, respectively. (PDF 107 kb

Additional file 7: of Epigenetics of amphetamine-induced sensitization: HDAC5 expression and microRNA in neural remodeling

https://figshare.com/articles/Additional_file_7_of_Epigenetics_of_amphetamine-induced_sensitization_HDAC5_expression_and_microRNA_in_neural_remodeling/4398842

Additional file 4: of Epigenetics of amphetamine-induced sensitization: HDAC5 expression and microRNA in neural remodeling

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