Simple generalized reaction conditions for the conversion of primary aliphatic amines to surfactant-like guanidine salts with 1<i>H</i>-pyrazole carboxamidine hydrochloride

Abstract

<p>Improved reaction conditions for the electrophilic reaction between a free aliphatic amine and 1H-pyrazole carboxamidine have been discovered. The surfactant-like guanidine salts, which are often hard to work with, were obtained in decent yields with short reaction times, minimal workup, and high level of purity.</p