Co-culture experiments of ECFCs (green colored) and SPCs (red colored) (original magnification ×100).

Abstract

<p>(A) In co-culture system (n = 7 for each group), both ECFCs and SPCs contribute to the tube formation. (B and C) MMD ECFCs when co-cultured with either normal SPCs or MMD SPCs make significantly less number of tubes than normal ECFCs (p = 0.168 for [normal ECFCs + normal SPCs] vs. [normal ECFCs + MMD SPCs]; p<0.001 for [normal ECFC+ normal SPC] vs. [MMD ECFC+ normal SPC]; p<0.001 for [normal ECFC+ normal SPC] vs. [MMD ECFC+ MMD SPC]).</p