<i>In vivo</i> reactive oxygen species (ROS)-imaging with L-012 after incision in rats.

Abstract

<p>(A) Examples of <i>in vivo</i> imaging after gastrocnemius muscle incision. (B) Average luminescence intensity in <i>in vivo</i> ROS-imaging on gastrocnemius muscle incision, gastrocnemius incision with catalase (1,000–2,500 IU), skin-only incision, and sham. The results are presented as mean and SEM for 6 rats in each group. * P < 0.0001 compared with sham, † P < 0.0001 compared with gastrocnemius incision with catalase, ‡ P < 0.0001 compared with skin-only incision, # P < 0.0001 compared with sham, § P = 0.0159 compared with gastrocnemius incision with catalase, & P = 0.0490 compared with skin-only incision, ¶ P = 0.0166 compared with sham. Two-way ANOVA (interaction factor: F<sub>6, 30</sub> = 22.56, P < 0.0001) followed by Bonferroni's post hoc tests.</p

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