The interaction network of genera in enterotype 1. (a) The main contributor in enterotype 1 is shown with yellow circle (Prevotella), genera shown by white circles link to it directly, and red ones indirectly. Edges between nodes in red denote Spearman’s correlation > 0.4, and correlation ≤0.4 is in blue. The width of edges is scaled by correlation index. (b) The twelve genera negatively correlated with Prevotella are all decreased in enterotype 1. Box plots are shown to compare the relative abundances of genera within the interaction network of enterotype 1. Ten out of twelve genera are significantly decreased in enterotype 1. Boxes represent the inter quartile ranges, lines inside the boxes denote medians, and circles are outliers. +, adjust P value <0.01; ns, not significant. Wilcoxon rank sum test. (PDF 547 kb
