Additional file 2: Figure S1. of Deletion of the Ste20-like kinase SLK in skeletal muscle results in a progressive myopathy and muscle weakness

Abstract

SLK knockout mice display reduced body mass, muscle size, but show no increase in fibrosis. (A) Body mass of wild type and knockout littermates was measured from 4 weeks to 22 weeks (n = 5/genotype). (B) Fiber cross-sectional area was measured in wild type and knockout mice at 3 and 24 weeks (n = 5/genotype). (C) Western blot for markers of fibrosis and atrophy on 6-month-old skeletal muscle lysates. (D, E) Masson’s trichome staining on 6-month-old skeletal muscle cross sections from wild type and knockout muscle. (TIF 5209 kb