Additional file 1: Figure S6. of 3D: diversity, dynamics, differential testing – a proposed pipeline for analysis of next-generation sequencing T cell repertoire data
Results of all ipilimumab treated prostate caner subjects and separately by long survivors (overall survival > = 23.6 months) and short survivors (overall survival < 23.6 months). (A) Shannon index of TCR at Week 0 and Week 2. (B) Clonality of TCR at Week 0 and Week 2. (C) intraclass correlation coefficient of TCR between Week 0 and Week 2. (D) Morisita’s distance of TCR between Week 0 and Week 2. (E) Scatter plot of Shannon vs. log10(# of uniques). Pearson correlation coefficient and corresponding pvalues were calculated. (F) Scatter plot of Clonality vs. log10(# of uniques). Pearson correlation coefficient and corresponding pvalues were calculated. (PDF 2080 kb
