CMV infection decreases TER of polarized HCoEpiC.

Abstract

<p>At 6 days after plating, polarized HCoEpiC were inoculated with CMV VR1814 from the apical surface at a MOI of 1.0 (<b>A</b>), from the basolateral surface at a MOI of 10 (<b>B</b>), or mock-infected. TER was then measured by Millicell-ERS every 3 days. The shaded area (gray) indicates TER of nonpolarized cells (<100 Ohm*cm<sup>2</sup> as confirmed by FITC-dextran leakage). Data are shown as the mean ± SEM with n = 5 for each experimental condition. Statistical comparison was performed by the Mann Whitney U-test and was considered significant at (<b>A</b>) **P<0.01 and (<b>B</b>) *P<0.05.</p

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