<p>A. Sham group; B. Model group; C. Treatment (picroside II) group; D. Positive control (apocynin) group; E. Treatment + Positive control (picroside II + apocynin) group; F. Agonist (TBCA) group; G. Agonist + Treatment (TBCA + picroside II) group; H. Vehicle (DMSO) group. ***<i>P</i><0.001 compared to group A; ## <i>P</i><0.01 compared to group B; ### <i>P</i><0.001 compared to group B; △△<i>P</i><0.01 compared to group F. The data were compared with one-way ANOVA; Values are presented as means ± SD; n = 5.</p