MOESM1 of Interference of retroviral envelope with vaccine-induced CD8+ T cell responses is relieved by co-administration of cytokine-encoding vectors

Abstract

Additional file 1: Figure S1. Experimental layout. CB6F1 mice were immunized with 25 µg plasmid DNA each encoding Leader-Gag, Leader-Gag and Env, or Leader-Gag, Env and a cytokine. Antibody and CD8+ T cell responses were analysed two weeks after immunization. Three weeks after immunization, mice were challenged with 5000 SFFU FV, and plasma and spleen viral loads were analysed ten days and 21 days after FV infection, respectively