Comparison of total distribution volume (<i>V</i><sub><i>T</i></sub>) between healthy controls and PD patients calculated with ASIF and PBIF75 for putamen (left) and caudate (right).

Abstract

<p>Estimation with PBIF75 led to same conclusion as with the ASIF; that there is no difference from disease (p = 0.2 in Caudate and p = 0.8 in the Putamen using PBIF vs p = 0.4 in Caudate and p = 0.7 in Putamen using ISIF) and that there is a difference due to genotype (p = 0.001 in Caudate and p = 0.002 in Putamen using PBIF vs p = 0.001 in the Caudate and p = 0.0008 in Putamen using ASIF). Images were partial volume effect corrected prior to TAC extraction.</p

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