<p>Mice were injected with braylin (BRA; 50 mg/kg), vehicle (50% propylene glycol in saline; control group) or dexamethasone (Dexa; 2 mg/kg; reference drug) by ip route 40 minutes before CFA (injected at time zero). The naïve group consists of mice that did not receive any experimental manipulation. Panels shows the paw levels of (A) interleukin-1β (IL-1β), (B) tumor necrosis factor-α (TNF-α), (C) interleukin-6 (IL-6), (D) interleukin-13 (IL-13), (E) interleukin-10 (IL-10) and (F) transforming growth factor-β (TGF-β), determined in skin tissues samples by ELISA, 3 hours after the CFA injection. The results are expressed as picograms of cytokine per milligram of protein. Data are expressed as means ± SEM; <i>n</i> = 6 mice per group. * Significantly different from the vehicle group in the same time (<i>p</i> < 0.05); <sup>#</sup> significantly different from the naive group (<i>p</i> < 0.05). ANOVA followed by Tukey´s multiple comparison test.</p
