Microbiological control and antibacterial action of a propolis-containing mouthwash and control of dental plaque in humans

Abstract

<p>Propolis is a bee product with several biological properties. This study aimed at investigating a propolis-containing mouthwash, its organoleptic properties, microbial contamination and its antibacterial action <i>in vitro</i>. This mouthwash was assessed <i>in vivo</i> to control dental plaque in humans. The presence of microorganisms was analyzed and the minimum inhibitory concentration against <i>Streptococcus mutans</i> was determined. A comparative study was done <i>in vivo</i> using propolis, chlorhexidine, and propolis plus chlorhexidine in lower concentrations for 14 days. Dental plaque was analyzed by the Patient Hygiene Performance (PHP) index. The odontological product was yellow, cloudy, free of microbial contamination, and exerted an inhibitory action <i>in vitro</i>. Individuals who used a propolis-containing mouthwash for 14 consecutive days in combination or not to chlorhexidine showed a similar PHP index to chlorhexidine alone. The product exerted an antibacterial action <i>in vitro</i> and <i>in vivo</i>, exhibiting a positive action in the control of dental plaque.</p