M2 antigen expression modulates splenic B cell activation and differentiation in vivo.

Abstract

<p>The transduced adoptively transferred B cell populations from M2 and M2.stop animals were analyzed for cell surface marker expression as a function of transgene expression. Data is representative of two independent experiments with 3 mice/group. A) Representative histogram depicting Thy1.1 expression within the adoptively transferred (CD45.1+) population in M2 and M2.stop animals at D5 post transfer. Thy1.1 expression in the CD45.1+ fraction was divided into Thy1.1 –, Thy1.1 Lo/Int (or Thy1.1 +), and Thy1.1 Hi populations. Representative histograms displaying B cell surface marker expression and intracellular IL10 production corresponding to Thy1.1 expression intensities are displayed for M2 (B) and M2.stop (C) transduced B cells.</p

    Similar works

    Full text

    thumbnail-image

    Available Versions