Abstract

<p>CD49a expression on bulk, CD56<sup>dim</sup> and CD56<sup>bright</sup> NK cells in the liver transplantation cohort <b>(A)</b> and in the tumor-free liver resection cohort <b>(B)</b>. Proportion of cells expressing specific markers in ihNK cells once gated on CD49a+ and CD49a- NK cells in the liver transplantation cohort <b>(C)</b> with CD25+ (CD49a+ NK cell median (IQR): 14.7 (7.1–22.7); CD49a- NK cell median (IQR): 2.5 (1.6–3.8); p<0.0001), CD34+ (CD49a+NK cell median (IQR): 17.4 (10–24.1); CD49a- NK cell median (IQR): 6.8 (4.2–16.3); p = 0.0107) and CXCR3+ (CD49a+ NK cell median (IQR): 14.8 (8.1–19.4); CD49a- NK cell median (IQR): 4.5 (2.2–10); p = 0.0002). <b>(D)</b> Proportion of cells expressing specific markers in ihNK cells once gated on CD49a+ and CD49a- in tumor-free liver resections. All data is depicted as scatter plot, with each dot corresponding to a participant. Bars indicate median and IQR. Wilcoxon signed rank tests with adjustment of p-values by false discovery rate.</p

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