Additional file 1: of The analysis of APOL1 genetic variation and haplotype diversity provided by 1000 Genomes project

Abstract

Table S1. Size and function of APOL1 exons and introns. Table S2. The population and the number of samples in the different regions of people. Table S3. List of all SNP (MAF ≥ 1%) found in APOL1 gene region, their genomic positions on chromosome 22 and their allele frequencies presented in 1000 Genomes Project (Phase 3). Table S4. List of SNP (MAF ≥ 1%) found in APOL1 upstream regulatory region (URR), their genomic positions on chromosome 22 and their allele frequencies presented in 1000 Genomes Project (Phase 3). Table S5. List of SNP (MAF ≥ 1%) found in the APOL1 3′ untranslated region (3’UTR), their genomic positions on chromosome 22 and their allele frequencies presented in 1000 Genomes Project (Phase 3).Table S6. List of all SNP found in APOL1 coding region, their genomic positions on chromosome 22 and their allele frequencies presented in 1000 Genomes Project (Phase 3). Table S7. List of APOL1 coding haplotypes generated by Tag SNP (consider the two SNP of G1) which presenting a global frequency higher than 1%, considering all populations of the 1000 Genomes Project (Phase 3). Table S8. The most frequent APOL1 coding haplotypes and their frequencies (consider the two SNP of G1) among the 1000 Genomes Project (Phase 3) in different populations. Figure S1. Linkage disequilibrium plot generated by APOL1 gene SNPs (MAF ≥ 1%). Inter-SNP D’-values are displayed on the plot. Figure S2. 12 Tag SNP position in APOL1 gene. Figure S3. Spatial distribution of genetic variants at the APOL1 functional domain. (DOCX 531 kb

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