Putative binding sites of HOXD-AS1 and SOX4 with miR-130a-3p. (A) Expression of potential miRNAs in HCC in TCGA cohorts. (B) Comparison summary of miR-130a-3p target sites in HOXD-AS1 and SOX4. The red nucleotides (target sites) were deleted in the mutant constructs. (C) pGL3 luciferase reporter constructs containing wild type and mutated putative binding sites of HOXD-AS1 or SOX4 transcripts were shown. (TIF 1598Â kb