Kp determination by derivative spectroscopy and Stern Volmer plots of Daunorubicin using a DMPC:SM model system. from A biophysical approach to daunorubicin interaction with model membranes: relevance for the drug's biological activity

Abstract

Absorption (A) and third-derivative absorption (B) spectra of daunorubicin (40μM) (red line, 0) alone, incubated in DMPC:SM model membrane at 37 °C. Stern–Volmer plots of the probe DPH in the DMPC:SM model at pH 7.4 and 37 °C with increasing daunorubicin concentration

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