T-bet+ CD11c+ B cells are critical for antichromatin immunoglobulin G production in the development of lupus. Figure S1. The fraction of T-bet and CD11c positive population was increased in CD138+ plasma cells. Figure S2. Correlation between the percentage of T-bet+ CD11c+ CD19+ B cells and the titers of anti-ANA antibodies (A), anti-dsDNA antibodies (B) from 22 SLE patients. Figure S3. IFNÎł is required for T-bet+ CD11c+ B cell differentiation and activation. 5 Ă 107 splenocytes from Bm12 mice or B6 mice cells were injected intraperitoneally into B6 mice (n = 5). (PDF 361 kb
