Definition of clinical outcomes in the 19-year registry-based monitoring of the DCGP study, any diabetes related endpoint (list). (DOCX 76 kb

Andreas Heltberg (3823546)

Christina Ellervik (3823540)

Henrik BrĂ¸nnum-Hansen (4671031)

Jakob Kragstrup (3467705)

John Andersen (90301)

Niels de Fine Olivarius (575870)

Volkert Siersma (848218)

BMC Endocrine Disorders

Table S3. The effect of structured personal care on behavioral, clinical, process of care and biochemical variables according to employment status (out of labor market vs. in labor market, retired excluded) (DOCX 37 kb

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Additional file 4: of Socio-demographic determinants and effect of structured personal diabetes care: a 19-year follow-up of the randomized controlled study diabetes Care in General Practice (DCGP)

Additional file 1: of Socio-demographic determinants and effect of structured personal diabetes care: a 19-year follow-up of the randomized controlled study diabetes Care in General Practice (DCGP)

Table S2. The effect of structured personal care on behavioral, clinical, process of care and biochemical variables according to civil status (DOCX 37 kb

Additional file 3: of Socio-demographic determinants and effect of structured personal diabetes care: a 19-year follow-up of the randomized controlled study diabetes Care in General Practice (DCGP)

Heltberg, Andreas

Siersma, Volkert

Andersen, John Sahl

Ellervik, Christina

Brønnum-Hansen, Henrik

Kragstrup, Jakob

Olivarius, Niels de Fine

Copenhagen University Research Information System

English

Socio-demographic determinants and effect of structured personal diabetes care:a 19-year follow-up of the randomized controlled study diabetes Care in General Practice (DCGP)

Abstract Background We investigated how four aspects of socio-demography influence the effectiveness of an intervention with structured personal diabetes care on long-term outcomes. Methods The Diabetes Care in General Practice (DCGP) study is a cluster-randomized trial involving a population-based sample of 1381 patients with newly diagnosed type 2-diabetes mellitus. We investigated how education, employment, cohabitation status and residence influenced the effectiveness of 6 years of intervention with structured personal diabetes care, resembling present day recommendations. Outcomes were incidence of any diabetes-related endpoint and death during 19 years after diagnosis, and cardiovascular risk factors, behaviour, attitudes and process-of-care variables 6 years after diagnosis. Results Structured personal care reduced the risk of any diabetes-related endpoint and the effect of the intervention was modified by geographical area (interaction p = 0.034) with HR of 0.71 (95%CI: 0.60–0.85) and of 1.07 (95%CI: 0.77–1.48), for patients in urban and rural areas, respectively. Otherwise, there was no effect modification of education, employment and civil status on the intervention for the final endpoints. There were no noticeable socio-demographic differences in the effect of the intervention on cardiovascular risk factors, behaviour, attitudes, and process-of-care. Conclusion Structured personal care reduced the aggregate outcome of any diabetes-related endpoint and independent of socio-demographic factors similar effect on cardiovascular risk factors, behaviour, attitudes and process of care, but the intervention did not change the existing inequity in mortality and morbidity. Residence modified the uptake of the intervention with patients living in urban areas having more to gain of the intervention than rural patients, further investigations is warranted. Trial registration ClinicalTrials.gov registration no. NCT01074762 (February 24, 2010)

Andreas Heltberg

Volkert Siersma

John Sahl Andersen

Christina Ellervik

Henrik Brønnum-Hansen

Jakob Kragstrup

Niels de Fine Olivarius

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Socio-demographic determinants and effect of structured personal diabetes care: a 19-year follow-up of the randomized controlled study diabetes Care in General Practice (DCGP)

Table S4. The effect of structured personal care on behavioral, clinical, process of care and biochemical variables according to residence (Rural vs. Urban) (DOCX 37 kb

Additional file 5: of Socio-demographic determinants and effect of structured personal diabetes care: a 19-year follow-up of the randomized controlled study diabetes Care in General Practice (DCGP)

Table S1. The effect of structured personal care on behavioral, clinical, process of care and biochemical variables according to level of education (DOCX 35 kb

Additional file 2: of Socio-demographic determinants and effect of structured personal diabetes care: a 19-year follow-up of the randomized controlled study diabetes Care in General Practice (DCGP)

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Additional file 1: of Socio-demographic determinants and effect of structured personal diabetes care: a 19-year follow-up of the randomized controlled study diabetes Care in General Practice (DCGP)

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