Injection of Substance P boosts motor learning.

Abstract

<p>Injecting 1 μl Sub P into M1 before training session 1–3 (black arrows) significantly improves the performance gain when compared to controls. Injecting the same amount of Substance P to a time-point when animals reached plateau (grey arrows) has no effect. Thus, Substance P affects the acquisition but not execution of a skilled reaching task. Values are presented as mean ± SEM.</p