Chang-Seok Ki (63002)

Keunjung Heo (4721832)

Min-Jung Lee (279000)

Minyeop Nahm (121038)

Seung Kim (486369)

Seungbok Lee (104462)

Young-Eun Kim (179629)

Gallica, Bibliotheque Numerique

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Progressive apoptotic cell death in gef26 knockdown brains and reduced locomotor activities of flies transheterozygous for gef26 and rap1 or dad. a and b Neuron-specific knockdown of gef26 expression causes age-dependent apoptotic cell death in the adult brain. a Confocal slices of 20-day-old C155-GAL4/+ and C155-GAL4/+; UAS-gef26 RNAi /+ brains labeled with TUNEL and DAPI. Scale bars, 20 μm. b Quantification of TUNEL-positive cells in three consecutive, middle frontal sections (5 μm thick) of C155-GAL4/+ and C155-GAL4/+; UAS-gef26 RNAi /+ brains. n = 4. c and d Reduced locomotor activities of flies transheterozygous for gef26 and rap1 or dad. c Distribution of the distance climbed by 30-day-old flies of the indicated genotypes over a 30 s period. d Quantification of average climbing distance for the genotypes indicated. All comparisons are with the C155-GAL4/+ control (b) or wild type (d): *P < 0.001. (TIFF 21040 kb

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Additional file 11: Figure S4. of The Rap activator Gef26 regulates synaptic growth and neuronal survival via inhibition of BMP signaling

https://figshare.com/articles/Additional_file_11_Figure_S4_of_The_Rap_activator_Gef26_regulates_synaptic_growth_and_neuronal_survival_via_inhibition_of_BMP_signaling/5738859

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Gallica, Bibliotheque Numerique

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