Many investigations have addressed the possibility of using multipotent
mesenchymal stromal cells (MSCs) for treatment of various
diseases due to their ability for tissue regeneration and unique
immunomodulating capacities. These stromal cells can be
cultivated in vitro and represent adult, fibroblast-like cells that
can differentiate into tissues of mesodermal origin. Previous
studies have attempted to develop the criteria for human MSC
eligibility for therapeutic applications. MSCs secrete various
cytokines, growth factors and extracellular matrix molecule
