Hierarchical clustering dendrogram based on SOD1âs SEA. (EPS 48Â kb

Nikita Ivanisenko (472058)

Nikolay Alemasov (4823547)

Srinivasan Ramachandran (4979)

Vladimir Ivanisenko (4823550)

BMC Structural Biology

PDB file A. SOD1 X-ray structure (PDBID: 2V0A) with b-factors being set to values of mechanical stiffness, ÎşCu,i, between the copper ion of chain A and residues of SOD1. (PDB 342Â kb

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Additional file 4: of Molecular mechanisms underlying the impact of mutations in SOD1 on its conformational properties associated with amyotrophic lateral sclerosis as revealed with molecular modelling

Additional file 2: Figure S1. of Molecular mechanisms underlying the impact of mutations in SOD1 on its conformational properties associated with amyotrophic lateral sclerosis as revealed with molecular modelling

Table of hydrogen bondsâ SEA. (XLSX 116Â kb

Additional file 1: Table S1. of Molecular mechanisms underlying the impact of mutations in SOD1 on its conformational properties associated with amyotrophic lateral sclerosis as revealed with molecular modelling

A relationship between the normalized thermostability of SOD1 mutants studied within the current work and their clinical effect expressed as survival time of an ALS patient with a corresponding SOD1 mutation. All thermostability values and survival times were taken from the literature [16]. (EPS 71Â kb

Additional file 7: Figure S2. of Molecular mechanisms underlying the impact of mutations in SOD1 on its conformational properties associated with amyotrophic lateral sclerosis as revealed with molecular modelling

PDB file F. SOD1 X-ray structure (PDBID: 2V0A) with b-factors being set to values of mechanical stiffness, ÎşCu,i, between the copper ion of chain F and residues of SOD1. (PDB 342Â kb

Additional file 5: of Molecular mechanisms underlying the impact of mutations in SOD1 on its conformational properties associated with amyotrophic lateral sclerosis as revealed with molecular modelling

Table H with Îž j m $$ {\xi}_j^m $$ distribution. (XLSX 6Â kb

Additional file 3: Table S2. of Molecular mechanisms underlying the impact of mutations in SOD1 on its conformational properties associated with amyotrophic lateral sclerosis as revealed with molecular modelling

https://figshare.com/articles/Additional_file_4_of_Molecular_mechanisms_underlying_the_impact_of_mutations_in_SOD1_on_its_conformational_properties_associated_with_amyotrophic_lateral_sclerosis_as_revealed_with_molecular_modelling/5857506

Additional file 2: Figure S1. of Molecular mechanisms underlying the impact of mutations in SOD1 on its conformational properties associated with amyotrophic lateral sclerosis as revealed with molecular modelling

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