Ethanolic extract of mahkota dewa fruit (Phaleria macrocarpa (Scheff.)
Boerl) has a content of flavonoid, saponin and tannin as antibacterial. Ethanolic
extract should be formulated in cream to make it easier function. This present
study aimed to determine difference proportion of cetaceum and cera alba on
physical characteristics, physical stability cream and antibacterial activity
Staphylococcus epidermidis.
Mahkota dewa fruit was conducted by soxhletation using ethanol 96%. The
evaluation of cream consisted of viscosity, pH, spread ability, adhesiveness,
physical stability with freeze thaw cycling and antibacterial with diffusion
method. Antibacterial activity could be seen from the resulting inhibition zone.
Analyzing of data used anova to know the effect compare proportion of cetaceum
and cera alba to the physical characteristic, multivariate test to know physical
stability of the cream and paired sample t-test to know the effect freeze thaw
cycling to antibacterial activity.
The results showed that there was proportion of cetaceum and cera alba on
formula affected the viscosity, adhesiveness, and spread ability showed p-value
<0,05. Physical stability with freeze thaw cycling method showed a steady to
cycle 2. Antibacterial activity of cream ethanolic extract mahkota dewa
unchanged after freeze thaw cycling
