Kemp, Stephen J.

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Centre for Tropical Livestock Genetics and Health (CTLGH)Steve Kemp, ILRITropAg2017 Conference, Brisbane, 20-22 November 2017A place for livestock ! The big picture and Our joint commitmentThe SDGs: the next 15 yearsTools, Resources and Solutions  (to improve livestock in tropical small holder systems)DiscoverDevelopDeliverA partnership for livestock development (innovation and impact)CTLGH operations(Edinburgh,Nairobi)Centre for Tropical Livestock Genetics and Health – CTLGH • £10M foundational investment (BMGF) • £4M supplement funding (DFID)• GCRF data and resources• GCRF impact accelerator account Strategic goal:CTLGH: The leading livestock R&D Centre poised to tackle tropical livestock development challenges (“omics”-based solutions).Current operations: Development of genomic tools to improve the productivity, efficiency, resilience, and health of tropical livestock owned by smallholder farmers2015 - 2022Key CTLGH/ILRI partnershipsKind Palms VenturesOlorunOsun FarmsACGG partnershipsHarnessing genetic variability among indigenous and exotic breeds of cattle (as well as their crosses) to develop genetic and genomic tools that will be used to improve productivity under harsh tropical conditions and to mitigate the impact of cattle on climate change.Harnessing genetic variability in tropical productivity and adaptation among various breeds of Chickens.Development and application of precision breeding (through novel reproductive and germplasm technologies) to achieve step changes in livestock genetic improvement. Understanding the genetic and molecular mechanisms underlying tolerance of certain cattle and poultry breeds to tropical diseases and pests.A shared global data and biological sample resource to support continued research and development on tropical livestock genetics and health.Current programsDual purposeimmune competencyFeed conversionefficient AdaptableLikeable OptionsBy context DiversityThe teamNick Spark, Georgios Banos, Dessie Tadelle, Olivier Hanotte, Jacqueline Smith, Almas Gheyas and others …Investigators: Mike McGrew (RI), Bruce Whitelaw (RI)Steve Kemp (ILRI)Objectives1. Biobank indigenous African fowl (in an Africa biobank)2. Develop and share tools for gene editing chicken and dairy cattle3. Produce a gene edited livestock with increase productivity, environmental/disease resilienceIndigenous chicken embryoIndigenous breedxA high throughput biobank of African indigenous breedsSterile	HostInnovate	UK:	Cobb	VantressConstruction of disease resilient animals“A knowledge base upon which to establish the selection or construction of disease resilient animals and effective disease interventions adapted to African farming systems”InvestigatorsCoordinatorsMark	BronsvoortLiam	MorrisonTimConnellyJames	PrendergastIvanMorrisonPhil	ToyeMusa	HassanFellowsMaurine	ChepkwonyRebecca	CallabyAnnieCookHannekeHemminkDavidWragPerle de	LatreTolerance to Theileria parva infectionCo-Leaders: Mick Watson (RI), Steve Kemp (ILRI)Ongoing activities and available resources• Hundreds of genomes have now been processed: African cattle, African buffalo, African chickens, African sheep and goats, chicken microbiomes, African warthogs• Assessing population diversity• Genome assemblies being carried (N’dama, Indian Water Buffalo, African warthogs)CyVerseAfricaResearch capacity and data infrastructure to power the advancement of open practices in African bioscienceCTLGH: Emerging opportunities• Research collaborations – leveraging current investments and ongoing projects• Resource mobilization – UK, Europe, Africa, US, Australia• Capacity building – research skills gaps (South & North)• CTLGH 10-years strategy – Under developmentwww.ctlgh.orgCTLGH: Improving tropical livestock productivity and resilienceappolinaire.djikeng@ctlgh.orgappolinaire.djikeng@roslin.ac.ed.uk

Centre for Tropical Livestock Genetics and Health (CTLGH)

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Centre for Tropical Livestock Genetics and Health (CTLGH)

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