Diamond, Dermot

Matzeu, Giusy

Zuliani, Claudio

English

DCU Online Research Access Service

UNIVERSITY COLLEGE DUBLIN      DUBLIN CITY UNIVERSITY      TYNDALL NATIONAL INSTITUTE  Towards Wearable Sensors for Wireless pH Monitoring in Sweat Giusy Matzeu, Claudio Zuliani, Dermot Diamond  Clarity, Centre for Sensor Web Technology, Dublin City University, Ireland Pittcon, 14/03/2012 1 UNIVERSITY COLLEGE DUBLIN      DUBLIN CITY UNIVERSITY      TYNDALL NATIONAL INSTITUTE  2 UNIVERSITY COLLEGE DUBLIN      DUBLIN CITY UNIVERSITY      TYNDALL NATIONAL INSTITUTE  Analyte Chemo/Bio Sensing  Wireless data transmission  Sensors for the Digital World 4 UNIVERSITY COLLEGE DUBLIN      DUBLIN CITY UNIVERSITY      TYNDALL NATIONAL INSTITUTE  IS-Membrane Conducting Polymer Carbon Resist Silver PET Substrate   Cost   Reproducibility   Compatible with Wearable & Environmental Applications Sensors for the Digital World 5 UNIVERSITY COLLEGE DUBLIN      DUBLIN CITY UNIVERSITY      TYNDALL NATIONAL INSTITUTE  pH ISE – An Initial Design Sensors and Actuators B, 2010, 146 , 19 2nd calibration after 3days in the conditioning solution y = -53.3x + 537.1R² = 0.970y = -54.9x + 544.1R² = 0.972y = -53.2x + 504.8R² = 0.97301503004502 4 6 8 10E/ mVpHMay we improve this limit working on SPE fabrication ? 6 y = -52.1x + 521.2R² = 0.994y = -53.8x + 524.8R² = 0.996y = -52.0x + 519.7R² = 0.996y = -53.3x + 522.0R² = 0.99301503004502 4 6 8 10E/ mVpH1st calibration after overnight conditioning Loss of linearity & offset change over time.  UNIVERSITY COLLEGE DUBLIN      DUBLIN CITY UNIVERSITY      TYNDALL NATIONAL INSTITUTE  “Initial” vs “New” SPE 7 UNIVERSITY COLLEGE DUBLIN      DUBLIN CITY UNIVERSITY      TYNDALL NATIONAL INSTITUTE  “Original” vs “New” SPE -8-404-0.4 -0.2 0 0.2i/ uAE / VOriginal SPE y = 21.5x + 1.53R² = 0.986y = -52.4x - 0.21R² = 0.999-80-40040800 0.5 1i/ μAv0.5 / V0.5 s-0.50.3 < σ < 0.6 y = 71.9x + 1.27R² = 0.997y = -65.1x - 2.71R² = 0.996-80-40040800 0.5 1i/ μAv0.5 / V0.5s-0.5σ ≈ 1.6 8 -8-404-0.4 -0.2 0 0.2i/ AE / VNew SPE UNIVERSITY COLLEGE DUBLIN      DUBLIN CITY UNIVERSITY      TYNDALL NATIONAL INSTITUTE  pH ISEs – Silverless-SPE and Membrane Thickness 550 μm well allows a better reproducibility !  500 μm PMMA + 50 μm PSA as masking layer y = -52.8x + 521.0R² = 0.995y = -54.2x + 529.8R² = 0.996y = -53.6x + 522.2R² = 0.996y = -53.1x + 522.7R² = 0.995501502503503 5 7 9E / mVpH 175 μm PMMA + 50 μm PSA as masking layer y = -48.55x + 529.1R² = 0.988y = -52.6x + 530.8R² = 0.973y = -49.6x + 524.3R² = 0.989y = -57.0x + 572.3R² = 0.998501502503503 5 7 9E / mVpH10 Carbon prints were masked used PSA and PMMA.  PET substrate were laminated with  PSA and PMMA after that tracks carbon was screen printed: Integration of ISE within microfluidic system UNIVERSITY COLLEGE DUBLIN      DUBLIN CITY UNIVERSITY      TYNDALL NATIONAL INSTITUTE  pH ISEs – Performance over Time & Storage Calibration repeated after 5 days storage in conditioning solution  y = -55.2x + 563.5R² = 0.997y = -54.3x + 552.4R² = 0.997y = -57.9x + 579.0R² = 0.99501002003004003 4 5 6 7 8 9E/ mVpH11 Printing protocols, e.g., presence of Ag,, have a significant impact in sensor reproducibility over time ! y = -53.5x + 524.3R² = 0.996y = -55.8x + 565.0R² = 0.997y = -55.8x + 544.6R² = 0.99201002003004003 4 5 6 7 8 9E/ mVpH• Day 0 • Day 5 (kept in conditioning solution) • Day 19 (kept in dry conditions) Dry storage may preserve sensor functionality !    UNIVERSITY COLLEGE DUBLIN      DUBLIN CITY UNIVERSITY      TYNDALL NATIONAL INSTITUTE  Reference Electrodes based on Lipophilic Salts on SPE U. Mattinen, J. Bobacka, A. Lewenstam, Electroanalysis 2009, 21, 1955. -500-450-400-3500 20 40 60 80E/ mVTime / minSC=PEDOT  0.1 M KCl  1 mM KCl  1 mM NaCl  0.1 M NaCl  0.1 M KCl Cl- ≈ 20 mV/decade Possibility for RE where [Cl-] is constant Need optimisation • SC=PEDOT • SC=POT -250-200-150-100-500 20 40 60 80E/ mVTime / min 0.1 M KCl  1 mM KCl  1 mM NaCl  0.1 M NaCl  0.1 M KCl 13 UNIVERSITY COLLEGE DUBLIN      DUBLIN CITY UNIVERSITY      TYNDALL NATIONAL INSTITUTE  Mote Interface and Wireless Communication  2.53.03.54.00 20 40 60 80Potential / mVTime / s• Mote 1 • Mote 2 • Mote 3 • 16Ch-Lawson Labs   Bias between motes and standard instrumentation < 0.3mV   Bias between motes < 0.1 mV 14 UNIVERSITY COLLEGE DUBLIN      DUBLIN CITY UNIVERSITY      TYNDALL NATIONAL INSTITUTE  Dual SPE – Integration of pH & RE on same substrate   The two carbon disks printed on the PET substrate will be modified to give a pH and a reference electrode   The substrate can also be laminated with PSA and PMMA for futher integration within microfluidics. 15 Work currently under progress to optimize sensor response !! UNIVERSITY COLLEGE DUBLIN      DUBLIN CITY UNIVERSITY      TYNDALL NATIONAL INSTITUTE  Wearable pH Sensor –Concept Mote Casing Strap Patch Sensor + Microfluidic 16 UNIVERSITY COLLEGE DUBLIN      DUBLIN CITY UNIVERSITY      TYNDALL NATIONAL INSTITUTE  Wearable pH Sensor –Layers Microfluidics pH ISE & RE  Patch Mote Casing Mote 17 UNIVERSITY COLLEGE DUBLIN      DUBLIN CITY UNIVERSITY      TYNDALL NATIONAL INSTITUTE  Acknowledgements Prof. Dermot Diamond Dr. Fiachra Collins, postdoc Javier Torres, Tyndall Giusy Matzeu, PhD student Dr. Salzitsa Anastasova, Dr. Aleksandar Radu, Dr. Ulriika Mattinen,  Prof. Johan Bobacka 18 UNIVERSITY COLLEGE DUBLIN      DUBLIN CITY UNIVERSITY      TYNDALL NATIONAL INSTITUTE  SOCIAL/AGENCY COLLABORATORS INDUSTRY COLLABORATORS CSET CORE CLARITY Centre & Ecosystem 16 SOCIAL/AGENCY COLLABORATORS INDUSTRY COLLA ORATORS SOCIAL/AGENCY COLLABORATORS INDUSTRY COLLABORATORS 19 UNIVERSITY COLLEGE DUBLIN      DUBLIN CITY UNIVERSITY      TYNDALL NATIONAL INSTITUTE  Thank You for Attention 20 UNIVERSITY COLLEGE DUBLIN      DUBLIN CITY UNIVERSITY      TYNDALL NATIONAL INSTITUTE  pH ISEs – Role of SPE Design A comparison between 1° calibration for (Ag+C) SPE & C (Batch II) SPE  y = -51.9x + 519.6R² = 0.997y = -53.4x + 523.9R² = 0.99601002003004003 4 5 6 7 8 9E/ mVpH• (Ag+C) SPE • C SPE 12 

Towards wearable sensors for wireless pH monitoring in sweat

Name not available

http://doras.dcu.ie/16876/2/Pittcon_Final.pdf

Towards wearable sensors for wireless pH monitoring in sweat

Abstract

Similar works

Full text

Available Versions

DCU Online Research Access Service

Name not available