The theory of generalized Weyl algebras is used to study the 2Γ2
reflection equation algebra A=Aqβ(M2β) in
the case that q is not a root of unity, where the R-matrix used to define
A is the standard one of type A. Simple finite dimensional
A-modules are classified, finite dimensional weight modules are
shown to be semisimple, Aut(A) is computed, and the
prime spectrum of A is computed along with its Zariski topology.
Finally, it is shown that A satisfies the Dixmier-Moeglin
equivalence