To determine the effects of a virtual physical activity (PA) program in college students during social distancing due to COVID-19. 44 college students, male and female. Methods: Participants completed self-reported measures of the International Physical Activity Questionnaire, weekly PA, and a short-survey of the educational experience during social distancing. Participants completed the instruments at baseline and after 10-weeks of an on-line virtual PA program. Increased overall PA (p = 0.040) and transportation PA (p = 0.004), leisure-time PA (p = 0.031) domains increased following the program. The sitting time increased following the intervention (p = 0.0001). Students who failed to comply with at least 150 min/week of PA reduced the frequency of positive emotions compared to those who complied (p = 0.017). Social distancing and daily college tasks seem to lessen the effect of PA on sedentary behavior in college students regardless of an increase in PA