ABSTRACT: External radiation treatment (ERT) is one of the treatment methods against breast
cancer. As all therapies, radiation is linked with side effects. Utmost goal during the
treatment with radiation is to maximize the benefit for the patient (efficacy of the
treatment) while sparing other vital organs from radiation that could lead to organ’s
toxicity. The assessment of the overall benefit of a radiation treatment can be
modelled with the help of linear quadratic model. That model simulates the cell killing
for a specific type of cell (each cell cancerous or healthy has different properties:
radiosensitivity, proliferation) under a given radiation prescription and schema. With
the help of modelling, oncologists and medical physicists can simulate and predict
the outcome of a radiation treatment schema
