Modulating effects of bioactive water Naftussya from layers Truskavets' and Pomyarky on neuro-endocrine-immune complex and metabolism at rats exposed to acute stress

Abstract

Sydoruk Nadiya O, Gozhenko Anatoliy I, Zukow Walery. Modulating effects of bioactive water Naftussya from layers Truskavets’ and Pomyarky on neuro-endocrine-immune complex and metabolism at rats exposed to acute stress. Journal of Education, Health and Sport. 2016;6(11):715-730. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.227087 http://ojs.ukw.edu.pl/index.php/johs/article/view/4125 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755 (23.12.2015). 755 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Author (s) 2016; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 02.11.2016. Revised 22.11.2016. Accepted: 30.11.2016. MODULATING EFFECTS OF BIOACTIVE WATER NAFTUSSYA FROM LAYERS TRUSKAVETS’ AND POMYARKY ON NEURO-ENDOCRINE-IMMUNE COMPLEX AND METABOLISM AT RATS EXPOSED TO ACUTE STRESS Nadiya O Sydoruk1,2, Anatoliy I Gozhenko1,Walery Zukow3 1Ukrainian Scientific Research Institute of Transport Medicine Ministry of Health, Odesa [email protected] 2JSC “Dnipro-Beskyd”, Truskavets’, Ukraine [email protected] 3Faculty of Physical Education, Health and Tourism, Kazimierz Wielki University, Bydgoszcz, Poland [email protected] Abstracts Background. Previously we have been carry out integrated quantitative estimation of neuroendocrine, immune and metabolic responses to acute stress at male and female rats. The aim of this study is to compare the modulating effects of Bioactive Water Naftussya (BAWN) from layers Truskavets’ and Pomyarky on neuro-endocrine-immune complex and metabolism at rats exposed to acute stress. Materials and methods. The experiment is at white rats Wistar line. Rats were divided into intact and 5 test groups treated for seven days with tap (control) water, distilled water as well as table water "Truskavets’ka" and BAWN from Truskavets’ and Pomyarky layers. A day after the end of course animals test groups subjected to water immersion restraint stress. A day after stress determined HRV, endocrine, immune and metabolic parameters as well as gastric mucosa injuries and comparing them with parameters of intact animals. Results. BAWN both Truskavets’ and Pomyarky layers minimizes or obviates abnormal 15 parameters caused by stress, but does not affect the poststressory deviation of 7 parameters. On the other hand, BAWN causes deviation of 15 other parameters which little or do not change under stress. Distilled water and water "Truskavets’ka" affect some parameters the opposite way, other less favorable, but some more favorably than BAWN. Conclusion. BAWN both Truskavets’ and Pomyarky layers limit pathogenic effects of stress, and initiate or enhance its compensatory and sanogenic effects. Keywords: acute stress, HRV, hormones, immunity, metabolism, rats, bioactive water Naftussya