The circular economy is an economic model of production and consumption that involves reusing, repairing, refurbishing, and recycling materials after their service life. The use of waste as secondary raw materials is one of the actions to establish this model. Construction and demolition waste (CDW) constitute one of the most important waste streams in Europe due to its high production rate per capita. Aggregates from these recycling operations are usually used in products with low mechanical requirements in the construction sector. In addition, the incorporation of photocatalytic materials in construction has emerged as a promising technology to develop products with special properties such as air decontamination. This research aims to study the decontaminating behavior of mortars manufactured with the maximum amount of mixed recycled sand without affecting their mechanical properties or durability. For this, two families of mortars were produced, one consisting of traditional Portland cement and the other of photocatalytic cement, each with four replacement rates of natural sand by mixed recycled sand from CDW. Mechanical and durability properties, as well as decontaminating capacity, were evaluated for these mortars. The results show adequate mechanical behavior, despite the incorporation of mixed recycled sand, and improved decontaminating capacity by means of NOx reduction capacity