The Influence of Diabetes-related Distress on Depression
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Abstract
Depressive disorders in diabetic patients are nearly twice as likely
compared to the non-diabetic population. There is evidence that patients’
perception of diabetes is a decisive aspect of this association. Therefore this
study prospectively investigates the role of patients’ perceived diabetesrelated
distress on incidence depression and recovery.
343 patients with type 1 diabetes completed the CES-D and the Problem
Areas in Diabetes Scale (PAID) at baseline and at the 6-month follow-up. A
CES-D score of ≥16 indicated elevated depressive symptoms. A PAID score
of ≥30 indicated elevated diabetes-related distress. Logistic regression
analyses were performed with recovery from and incidence of depressive
symptoms as dependent variables. Independent variable was diabetesrelated
distress adjusted for possible demographic (age, gender, BMI) and
medical confounders (diabetes duration, HbA1c, insulin pump therapy, and
late complications).
At baseline 130 patients (37.9%) reported elevated depressive symptoms
and 40 of these patients (30.8%) recovered 6 months later. Of the 213 patients
without elevated depressive symptoms, 27 (12.7%) had elevated depressive
symptoms 6 months later. Diabetes-related distress at baseline diminished
the chance to recover from elevated depressive symptoms by 64% (OR =
0.36, p<.05). In addition, the chance for incident depressive symptoms if
diabetes-related distress was present at baseline is 2.5 times more likely in
contrast to no diabetes-related distress at baseline (OR=2.5; p<.05). In both
analyses, no other variables reached a signifi cant infl uence.
It could be demonstrated that preventing diabetes-related distress is a
protective factor regarding the incidence of elevated depressive symptoms.
Furthermore, preventing diabetes-related distress supports the recovery
from already elevated depressive symptoms. This supports the notion that
diabetes per se is not a risk factor for depressive disorders but the perceived
emotional distress is